性别差异与健康和肥胖的关系对青少年哮喘的风险
2016/08/31
摘要
目的：青少年女生和男生的体质与肥胖对哮喘风险的关系。
研究方法：一个横断面评估12-19岁的受试者根据1999-2004年全国健康和营养检查调查数据选出。受试者完成心肺功能测试、身质测量，与呼吸问卷调查。
结果：总共有4828名受试者参加了此项调查。在女孩中，超重/肥胖与既往哮喘（aOR 1.63，95% CI 1.16-2.30）、现在哮喘（aOR 1.73，95% CI 1.13，2.64）、以及喘息（aOR 1.40，95% CI 1.03-1.91）的比值比增加有关。超重/肥胖在女孩中也与哮喘发作（aOR 2.67，95% CI 1.56-4.65）和锻炼相关的喘息（aOR 1.60，95% CI 1.07-2.38）的比值比增加有关。在男孩中，身材健美与哮喘急诊访视（aOR 0.24，95% CI 0.07-0.89）、喘息相关就医（aOR 0.31，95% CI 0.13-0.75）、喘息相关误学（aOR 0.14，95% CI 0.06-0.33）、以及运动相关的喘息（aOR 0.43，95% CI 0.24-0.76）的比值比较低相关。
结论：超重/肥胖与哮喘的患病率和发病率增加在女孩中相关，但在男孩中不相关，与身材是否健美无关。身材健美与降低哮喘发病率在男孩中相关，但在女孩中不相关，与体重状态无关。肥胖和健美影响哮喘的发病和严重程度在男孩和女孩中可能通过不同的方式影响。
（杨冬 审校）
JPediatr. 2016 Jun 15.pii:S0022-3476(16)30258-X.doi:10.1016/j.jpeds.2016.05.050. [Epub ahead of print]
Sex Differences in the Relationship between Fitness and Obesity on Risk for Asthma in Adolescents.
Lu KD1, Billimek J2, Bar-Yoseph R3, Radom-Aizik S3, Cooper DM3, Anton-Culver H4.
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Abstract
OBJECTIVE:To evaluate the relationship of fitness and obesity on asthma risk in adolescent girls and boys.
STUDY DESIGN:A cross-sectional assessment of participants 12-19 years of age was conducted by the use of data from the 1999-2004 National Health and Nutrition Examination Survey. Participants completed cardiorespiratory fitness testing, body composition measurements, and respiratory questionnaires.
RESULTS:A total of 4828 participants were included. Overweight/obesity was associated with increased odds of history of asthma (aOR 1.63, 95% CI 1.16-2.30), current asthma (aOR 1.73, 95% CI 1.13, 2.64), and wheezing (aOR 1.40, 95% CI 1.03-1.91) in girls. Overweight/obesity also was associated with increased odds of asthma attacks (aOR 2.67, 95% CI 1.56-4.65) and wheezing related to exercise (aOR 1.60, 95% CI 1.07-2.38) in girls. High fitness was associated with lower odds of asthma-related visits to the emergency department (aOR 0.24, 95% CI 0.07-0.89), wheezing-related medical visits (aOR 0.31, 95% CI 0.13-0.75), wheezing-related missed days (aOR 0.14, 95% CI 0.06-0.33), and wheezing related to exercise (aOR 0.43, 95% CI 0.24-0.76) in boys.
CONCLUSION:Overweight/obesity is associated with increased asthma prevalence and morbidity in girls but not in boys, independent of fitness. High fitness is associated with decreased rates of asthma morbidity in boys but not in girls, independent of weight status. Obesity and fitness may each influence asthma onset and severity in different ways for girls compared with boys.
Copyright © 2016 Elsevier Inc. All rights reserved.
KEYWORDS:adolescents; asthma; fitness; obesity
JPediatr. 2016 Jun 15.pii:S0022-3476(16)30258-X.doi:10.1016/j.jpeds.2016.05.050. [Epub ahead of print]
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在妊娠期暴露于室外空气污染和儿童哮喘、过敏性鼻炎、湿疹
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父母孕期吸烟和戒烟对儿童哮喘的风险
