哮喘联盟

   摘要
   背景：哮喘在美国成人和儿童中是一个常见慢性疾病，导致每年近50万人住院治疗。自先前1988-2002年的研究数据以来，目前还没有评估美籍印度人(AI)/阿拉斯加原住民(AN)因哮喘住院治疗情况的研究。本研究描述了从2003-2011年AI/AN以及普通美国（US）人群哮喘住院治疗的趋势以及流行病学情况。
   方法：使用印度卫生服务(IHS)数据查阅2003-2011年AI/AN人群哮喘第一诊断的出院记录，使用国家住院患者样本查阅普通US人群。估算平均年粗略和年龄校正住院率。
   结果：AI/AN和美国US人群的平均年哮喘住院率2009-2011年(32%)较2003-2005年(11%)有所下降（标准误 (SE)为3%)，2009-2011年平均年校正年龄住院率AI/AN人群(7.6/10,000人口)低于普通US人群(13.2/10,000人口) (95% CI: 12.8-13.6)。1-4岁婴幼儿中年龄别AI/AN率最高。除阿拉斯加以外的所有地区的HIS地区率下降。
   结论：AI/AN人群和普通US人群哮喘住院率逐年减少，尽管患病率在逐年增加。与普通US人群相比，AI/AN人群具有较低的年龄校正哮喘住院率。虽然在AI/AN1-4岁婴幼儿中比率有大幅度下降，但仍然高于其他年龄组。改善疾病管理和认知有助于进一步降低哮喘住院率，尤其在年幼儿中。
 

（林江涛 审校）
Chest. 2014 May 8. doi: 10.1378/chest.14-0183. [Epub ahead of print]

 

Epidemiology of asthma hospitalizations among American Indian and Alaska Native people and the general United States population.
 

Mehal JM, Holman RC, Steiner CA, Bartholomew ML, Singleton RJ.
 

ABSTRACT
BACKGROUND：Asthma, a common chronic disease among adults and children in the United States, results in nearly half a million hospitalizations annually. There has been no evaluation of asthma hospitalizations for AI/AN people since a previous study using data for 1988-2002. In this study, we describe the epidemiology and trends for asthma hospitalizations among AI/AN people and the general US population for 2003-2011.
METHODS：Hospital discharge records with a first-listed diagnosis of asthma for 2003-2011 were examined for AI/AN people, using Indian Health Service (IHS) data, and for the general US population, using the Nationwide Inpatient Sample. Average annual crude and age-adjusted hospitalization rates were calculated.
RESULTS：The average annual asthma hospitalization rates for AI/AN people and the general US population decreased from 2003-2005 to 2009-2011 (32% and 11% [standard error (SE): 3%], respectively). The average annual age-adjusted rate for 2009-2011 was lower for AI/AN people (7.6/10,000 population) compared to the general US population (13.2/10,000, 95% CI: 12.8-13.6). Age-specific AI/AN rates were highest among infants and children 1-4 years of age. IHS regional rates declined in all regions except Alaska.
CONCLUSIONS：Asthma hospitalization rates are decreasing for AI/AN people and the general US population despite increasing prevalence rates. AI/AN people experienced a substantially lower age-adjusted asthma hospitalization rate compared to the general US population. While the rates for AI/AN infants and children 1-4 years of age have declined substantially, they remain higher compared to other age groups. Improved disease management and awareness should help to further decrease asthma hospitalizations, particularly among young children.
 

Chest. 2014 May 8. doi: 10.1378/chest.14-0183. [Epub ahead of print]