2002～2007年爱尔兰学龄期儿童哮喘、过敏性鼻炎和湿疹患病率趋势
2012/05/08
背景：爱尔兰青少年的哮喘发病率在全球居第三位。很少有试验研究爱尔兰年轻儿童哮喘和过敏性疾病的患病率趋势。我们比较了6～9岁的学龄期儿童2002年和2007年的哮喘、过敏性鼻炎和湿疹的患病率。
方法：在两次横断面研究中，分别于2002年（n=1474，回复率=74.8%）和2007年（n=1535，回复率=76.2%）对科克城24所学校的6～9岁儿童的父母进行ISAAC为基础的问卷调查。
结果：本研究中，6～9岁学龄期儿童的哮喘患病率自2002年以来维持稳定（2002年：21.7%；2007年：23.5%；p=0.27）。鼻结膜炎（7.6-10.6%, p=0.005）和湿疹（8.9-13.5%, p<0.001）的患病率存在显著上升。2007年，男性出现现患哮喘症状的人更多（M:F 1.2:1, p=0.075），但无统计学差异，而2002年男女儿童之间存在显著差异（M:F 1.5:1, p<0.001）。过敏性鼻炎相关症状的男女比例，从2002年的两者基本相等，变为男性更易出现这些症状（鼻部问题：2002 - M:F, 1.1:1, p=0.117; 2007 - M:F, 1.2:1, p=0.012；当前鼻炎：2002 - M:F 1.2:1, p=0.98; 2007 M:F 1.3:1, p=0.009；枯草热：2002 - M:F 1:1, p=0.57; 2007 - M:F 1.5:1, p=0.007）。鼻结膜炎和症状严重程度在两个时间段内男女基本平衡。从2002年至2007年，所有湿疹相关症状在男女儿童间无显著差异，而终身湿疹的患病率从男性较高转变为男女相似。
结论：科克城6～9岁学龄期儿童哮喘的患病率在2002年至2007年间基本平稳，而鼻结膜炎和湿疹的患病率存在增加。过敏性疾病共存给这些年轻群体带来了相当大的健康负担。我们结果表明，当前哮喘和终身过敏性鼻炎的患病率在男女儿童中趋向于一致。
（刘国梁 审校）Pediatr Allergy Immunol. 2012 Mar 22. doi: 10.1111/j.1399-3038.2012.01291.x. [Epub ahead of print]
The 2002-2007 trends of prevalence of asthma, allergic rhinitis and eczema in Irish schoolchildren.
Duggan EM, Sturley J, Fitzgerald AP, Perry IJ, Hourihane JO.
Source
Department of Paediatrics and Child Health, University College Cork, Cork, Ireland Department of Epidemiology and Public Health, Western Gateway Building, University College Cork, Cork, Ireland Department of Early Childhood Studies, Mary Immaculate College, Limerick, Ireland.
Abstract
BACKGROUND:Irish adolescents have the third highest asthma prevalence in the world. Few data examine trends of prevalence of asthma and allergic disorders in younger Irish children. We compared the prevalence of asthma, allergic rhinitis and eczema in school children, aged 6-9 in 2002 and 2007.
METHODS:In two cross-sectional studies, parents of children aged 6-9, completed identical ISAAC-based questionnaires in the same 24 Cork City schools in 2002 (n=1474, response rate=74.8%) and in 2007 (n=1535, response rate=76.2%).
RESULTS:The prevalence of asthma in our study population of schoolchildren, aged 6-9 remained stable in 2007 (23.5%) since the 2002 finding of 21.7% (p=0.27). Significant increases were found in the prevalence of rhino-conjunctivitis (7.6-10.6%, p=0.005) and eczema (8.9-13.5%, p<0.001). In 2007, male preponderance for suffering the symptoms of current asthma existed (M:F 1.2:1, p=0.075), although it had lost its significance since 2002 (M:F 1.5:1, p<0.001). M:F ratio for most allergic rhinitis related symptoms moved from equal sex distribution to male predominance (nasal problems ever: 2002 - M:F, 1.1:1, p=0.117; 2007 - M:F, 1.2:1, p=0.012, current rhinitis: 2002 - M:F 1.2:1, p=0.98; 2007 M:F 1.3:1, p=0.009, hay fever ever: 2002 - M:F 1:1, p=0.57; 2007 - M:F 1.5:1, p=0.007). The sex-specific prevalence of rhino-conjunctivitis and the severity of symptoms suffered, remained equally sex distributed in both timeframes. From 2002 to 2007, the prevalence of all the reported symptoms of eczema were equally distributed between the sexes, while lifetime prevalence of eczema moved from male predominance to equal distribution.
CONCLUSION:The prevalence of asthma in 6-9 yr old Cork schoolchildren remained static between 2002 and 2007; however, rhino-conjunctivitis and eczema have become increasingly prevalent. Co-morbidity of allergic conditions continues to pose a considerable health burden in this young population. We also demonstrated an alteration in the sex-specific profile of current asthma and lifetime allergic rhinitis towards equalization in distribution.
Pediatr Allergy Immunol. 2012 Mar 22. doi: 10.1111/j.1399-3038.2012.01291.x. [Epub ahead of print]
方法：在两次横断面研究中，分别于2002年（n=1474，回复率=74.8%）和2007年（n=1535，回复率=76.2%）对科克城24所学校的6～9岁儿童的父母进行ISAAC为基础的问卷调查。
结果：本研究中，6～9岁学龄期儿童的哮喘患病率自2002年以来维持稳定（2002年：21.7%；2007年：23.5%；p=0.27）。鼻结膜炎（7.6-10.6%, p=0.005）和湿疹（8.9-13.5%, p<0.001）的患病率存在显著上升。2007年，男性出现现患哮喘症状的人更多（M:F 1.2:1, p=0.075），但无统计学差异，而2002年男女儿童之间存在显著差异（M:F 1.5:1, p<0.001）。过敏性鼻炎相关症状的男女比例，从2002年的两者基本相等，变为男性更易出现这些症状（鼻部问题：2002 - M:F, 1.1:1, p=0.117; 2007 - M:F, 1.2:1, p=0.012；当前鼻炎：2002 - M:F 1.2:1, p=0.98; 2007 M:F 1.3:1, p=0.009；枯草热：2002 - M:F 1:1, p=0.57; 2007 - M:F 1.5:1, p=0.007）。鼻结膜炎和症状严重程度在两个时间段内男女基本平衡。从2002年至2007年，所有湿疹相关症状在男女儿童间无显著差异，而终身湿疹的患病率从男性较高转变为男女相似。
结论：科克城6～9岁学龄期儿童哮喘的患病率在2002年至2007年间基本平稳，而鼻结膜炎和湿疹的患病率存在增加。过敏性疾病共存给这些年轻群体带来了相当大的健康负担。我们结果表明，当前哮喘和终身过敏性鼻炎的患病率在男女儿童中趋向于一致。
（刘国梁 审校）Pediatr Allergy Immunol. 2012 Mar 22. doi: 10.1111/j.1399-3038.2012.01291.x. [Epub ahead of print]
The 2002-2007 trends of prevalence of asthma, allergic rhinitis and eczema in Irish schoolchildren.
Duggan EM, Sturley J, Fitzgerald AP, Perry IJ, Hourihane JO.
Source
Department of Paediatrics and Child Health, University College Cork, Cork, Ireland Department of Epidemiology and Public Health, Western Gateway Building, University College Cork, Cork, Ireland Department of Early Childhood Studies, Mary Immaculate College, Limerick, Ireland.
Abstract
BACKGROUND:Irish adolescents have the third highest asthma prevalence in the world. Few data examine trends of prevalence of asthma and allergic disorders in younger Irish children. We compared the prevalence of asthma, allergic rhinitis and eczema in school children, aged 6-9 in 2002 and 2007.
METHODS:In two cross-sectional studies, parents of children aged 6-9, completed identical ISAAC-based questionnaires in the same 24 Cork City schools in 2002 (n=1474, response rate=74.8%) and in 2007 (n=1535, response rate=76.2%).
RESULTS:The prevalence of asthma in our study population of schoolchildren, aged 6-9 remained stable in 2007 (23.5%) since the 2002 finding of 21.7% (p=0.27). Significant increases were found in the prevalence of rhino-conjunctivitis (7.6-10.6%, p=0.005) and eczema (8.9-13.5%, p<0.001). In 2007, male preponderance for suffering the symptoms of current asthma existed (M:F 1.2:1, p=0.075), although it had lost its significance since 2002 (M:F 1.5:1, p<0.001). M:F ratio for most allergic rhinitis related symptoms moved from equal sex distribution to male predominance (nasal problems ever: 2002 - M:F, 1.1:1, p=0.117; 2007 - M:F, 1.2:1, p=0.012, current rhinitis: 2002 - M:F 1.2:1, p=0.98; 2007 M:F 1.3:1, p=0.009, hay fever ever: 2002 - M:F 1:1, p=0.57; 2007 - M:F 1.5:1, p=0.007). The sex-specific prevalence of rhino-conjunctivitis and the severity of symptoms suffered, remained equally sex distributed in both timeframes. From 2002 to 2007, the prevalence of all the reported symptoms of eczema were equally distributed between the sexes, while lifetime prevalence of eczema moved from male predominance to equal distribution.
CONCLUSION:The prevalence of asthma in 6-9 yr old Cork schoolchildren remained static between 2002 and 2007; however, rhino-conjunctivitis and eczema have become increasingly prevalent. Co-morbidity of allergic conditions continues to pose a considerable health burden in this young population. We also demonstrated an alteration in the sex-specific profile of current asthma and lifetime allergic rhinitis towards equalization in distribution.
Pediatr Allergy Immunol. 2012 Mar 22. doi: 10.1111/j.1399-3038.2012.01291.x. [Epub ahead of print]
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母亲孕期进食与子女哮喘和过敏性疾病的相关性：来自芬兰的出生队列研究
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生物质和固体燃料燃烧造成的室内空气污染对印度成人男性和女性自我主诉的哮喘患病率的影响：来自国家性大规
