瑜伽是否有利于哮喘治疗？随机临床试验的系统综述
2011/10/13
摘要
目的：本项系统性综述旨在评价瑜伽作为哮喘治疗手段的有效性。
方法：对7个数据库2010年以前收录的信息进行检索。选出以各类瑜伽治疗哮喘的随机临床试验（RCT）和非随机临床试验（NRCT）进行分析。研究的选择、数据提取和验证均由2名作者独立完成。
结果：6项RCT和1项NRCT满足入选标准。大部分研究都存在方法学问题。有3项RCT和1项NRCT的结果表明，瑜伽能显著降低肺活量参数、降低气道高反应性、减少第一秒用力呼气体积下降20%的组胺剂量、减少每周哮喘发作次数和药物治疗需求。有3项RCT的瑜伽治疗与对照干预措施相比未见疗效。
结论：瑜伽能缓解哮喘的观点尚缺乏可靠依据，尚待更多严格的试验予以证实。
（林江涛 审校）
J Asthma. 2011 Aug;48(6):632-9. Epub 2011 May 31.
目的：本项系统性综述旨在评价瑜伽作为哮喘治疗手段的有效性。
方法：对7个数据库2010年以前收录的信息进行检索。选出以各类瑜伽治疗哮喘的随机临床试验（RCT）和非随机临床试验（NRCT）进行分析。研究的选择、数据提取和验证均由2名作者独立完成。
结果：6项RCT和1项NRCT满足入选标准。大部分研究都存在方法学问题。有3项RCT和1项NRCT的结果表明，瑜伽能显著降低肺活量参数、降低气道高反应性、减少第一秒用力呼气体积下降20%的组胺剂量、减少每周哮喘发作次数和药物治疗需求。有3项RCT的瑜伽治疗与对照干预措施相比未见疗效。
结论：瑜伽能缓解哮喘的观点尚缺乏可靠依据，尚待更多严格的试验予以证实。
（林江涛 审校）
J Asthma. 2011 Aug;48(6):632-9. Epub 2011 May 31.
Source
Department of Complementary Medicine, Peninsula Medical School, University of Exeter , Exeter , UK.
Department of Complementary Medicine, Peninsula Medical School, University of Exeter , Exeter , UK.
Abstract
OBJECTIVE： The objective of this systematic review was to assess the effectiveness of yoga as a treatment option for asthma.
METHOD： Seven databases were searched from their inception to October 2010. Randomized clinical trials (RCTs) and non-randomized clinical trials (NRCTs) were considered, if they investigated any type of yoga in patients with asthma. The selection of studies, data extraction, and validation were performed independently by two reviewers.
RESULTS： Six RCTs and one NRCT met the inclusion criteria. Their methodological quality was mostly poor. Three RCTs and one NRCT suggested that yoga leads to a significantly greater reduction in spirometric measures, airway hyperresponsivity, dose of histamine needed to provoke a 20% reduction in forced expiratory volume in the first second, weekly number of asthma attacks, and need for drug treatment. Three RCTs showed no positive effects compared to various control interventions.
CONCLUSIONS：The belief that yoga alleviates asthma is not supported by sound evidence. Further, more rigorous trials are warranted.
J Asthma. 2011 Aug;48(6):632-9. Epub 2011 May 31.
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