波多黎各儿童居住面积、出生地和哮喘的关系
2007/06/27
研究背景：在美国所有民族中，波多黎各人的哮喘患病率最高。目前还没有研究直接比较居住在波多黎各岛和美国大陆的波多黎各哮喘患者的相关差异。
目的：探讨波多黎各儿童出生场所，居住面积和患哮喘的关系。
方法：对居住在圣胡安，波多黎各岛的Caguas区和纽约Bronx区三个地区的儿童进行多阶大样本机率抽样分析。通过对2,491名儿童和他们的最主要看护者进行家庭调查获取数据资料。
结果：波多黎各儿童的哮喘总患病率最高(38.6%)。尽管来自波多黎各岛的波多黎各儿童具有较高的社会经济水平，较低的早产率和生前吸烟暴露率，但居住在波多黎各岛比居住在Bronx南部的波多黎各儿童的哮喘时间患病率高(分别41.3% 和35.3%, p = 0.01)。多因素分析显示：在波多黎各岛居住与较长的哮喘患病时间(似然比为1.27;95%可信区间, 1.03-1.57)和住院时间(OR, 1.47;95% CI, 1.04–2.07)有关。
结论：居住在波多黎各岛的比居住在Bronx区南部的波多黎各儿童患哮喘风险高。在研究在哮喘高危人群中哮喘的发病情况的同时还需要进一步研究探讨移民，文化交流及环境和社会心理等因素。
（于娜 中国医科大学附属一院呼吸科 110001 摘译)
(Chest. 2007;131:1331-1338)
(Chest. 2007;131:1331-1338)
Area of Residence, Birthplace, and Asthma in Puerto Rican Children
Robyn T. Cohen, MD, MPH; Glorisa J. Canino, PhD; Hector R. Bird, MD; Sa Shen, PhD; Bernard A. Rosner, PhD and Juan C. Celedón, MD, DrPH, FCCP
Abstract 摘要
Rationale: Puerto Ricans have the highest prevalence of asthma among all ethnic groups in the United States. There have been no studies that directly compare the burden of asthma between Puerto Ricans living in Puerto Rico and those living in the mainland United States
Objective: To examine the relation between birthplace, area of residence, and asthma in Puerto Rican children.
Methods: Multistage population-based probability sample of children in the San Juan and Caguas metropolitan areas in Puerto Rico and in the Bronx, NY. Information was collected in a household survey of 2,491 children and their primary caretakers.
Results: The overall prevalence of asthma among Puerto Rican children in this study was very high (38.6%). Although children from Puerto Rico had higher socioeconomic status and lower rates of premature birth and prenatal smoke exposure, the prevalence of lifetime asthma was higher in Puerto Rican children living in Puerto Rico than in Puerto Rican children living in the South Bronx (41.3% vs 35.3%, p=0.01). In multivariable analysis, residence in Puerto Rico was associated with increased odds of lifetime asthma (odds ratio [OR], 1.27; 95% confidence interval [CI], 1.03 to 1.57) and lifetime hospitalization for asthma (OR, 1.47; 95% CI, 1.04–2.07).
Conclusions: Puerto Rican children in Puerto Rico had a higher risk of asthma than Puerto Rican children in the South Bronx, highlighting the need for further examination of the roles of migration, acculturation, and environmental and psychosocial factors on the development of asthma in this high-risk population.
Key Words: asthma·prevalence·Puerto Ricans
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美国印地安成人哮喘
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两种遗传性结缔组织病与哮喘和气道塌陷
