在寻求戒烟治疗的年轻吸烟者中采用尼古丁替代治疗
2010/08/11
目的：在寻求戒烟治疗的城市年轻吸烟者中研究尼古丁替代治疗（NRT）。
设计：通过视频、电视和印刷宣传广告，募集研究参与者。对参与者采用预先筛选的问卷调查进行结构式访谈。
研究机构：受训者通过电话访谈收集吸烟者数据。
参与者：居住在巴尔的摩和马里兰州市区的、年龄为12～17岁的寻求戒烟的男性（38.2%）和女性（61.8%）共计1879名参与本研究。
干预措施：本项观察性研究未采用任何干预措施。
主要检测指标：通过对研究对象进行年龄、法格斯特伦尼古丁依赖测试（FTND）和种族进行分层后，研究受试者的NRT使用情况。
结果：研究对象的平均FTND 评分为5.7（SD=2.2）。大约有41％的吸烟者每天吸烟11～20支。采用NRT的年轻吸烟者，其年龄较未采用NRT的吸烟者年长，有统计学差异（15.9 vs 15.7岁; t-test= -2.60, P=0.01）。FTND 评分（检测尼古丁依赖的一个指标）在使用NRT的年轻人中较高（6.0 vs 5.6; t-test= -3.37, P= .001）。非洲裔美国人中，年轻吸烟者较相对应的欧洲裔美国年轻吸烟者较少使用NRT（33.0% vs 61.2%; chi2=16.09, P<.003）。通过逐步logistic回归分析，年龄、FTND 和种族是NRT使用的预测因子。
结论：我们结果显示不同年龄、不同FTND和不同种族年轻人群吸烟者中，其NRT使用存在差异。经过年龄和吸烟程度校正后，欧洲裔美国年轻吸烟者较其他相应人群吸烟者更常使用NRT，而非洲裔美国年轻吸烟者则较其他相应人群较少采用NRT。这些结果显示，在评价年轻吸烟者戒烟时，需考虑种族差异。对于造成这种差异的原因还需进一步进行研究，以便改善年轻吸烟者的戒烟。
（刘国梁 审校）
EthnDis.2010Spring;20(2):180-184.
Nicotine replacement therapy use among adolescent smokers seeking cessation treatment.
Botello-Harbaum M, Schroeder JR, Collins CC, Moolchan ET.
National Institutes of Health, National Institute of Child Health and Human Development, Intramural Research Program, USA.
Abstract
OBJECTIVE: To examine the correlates of prior nicotine replacement therapy (NRT) in an urban sample of adolescent smokers seeking smoking cessation treatment.
DESIGN: Adolescents were recruited via radio, TV and print advertisements for participation in treatment studies. Participants completed a structured interview using a prescreening questionnaire.
SETTING: Data were collected via a telephone interview by trained research personnel.
PARTICIPANTS: A sample (N=1879) cessation treatment-seeking volunteer boys (38.2%) and girls (61.8%) aged 12 to 17 years, from a diverse ethnic background residing in the Baltimore, Maryland metropolitan area.
INTERVENTIONS: No interventions were used in this observational study.
MAIN OUTCOME MEASURES: Use of NRT in adolescents stratified by age, Fagerstrom Test of Nicotine Dependence (FTND), and race/ethnicity.
RESULTS: The sample had a mean FTND score of 5.7 (SD = 2.2). About 41% smoked 11 to 20 cigarettes per day. Adolescent smokers who had used NRT were statistically but only marginally older than those who had not (15.9 vs 15.7 years; t-test= -2.60, P=0.01). FTND score, a measure of nicotine dependence, was higher among those who had used NRT (6.0 vs 5.6; t-test= -3.37, P= .001). African American adolescents were less likely to have used NRT than their European American counterparts (33.0% vs 61.2%; chi2=16.09, P<.003). After stepwise logistic regression analyses, age, FTND and race/ethnicity remained predictors of NRT use.
CONCLUSION: Our results show differences in NRT use patterns based on age, FTND, and race/ethnicity. European American youths are more likely than their ’other’ counterparts to use NRT, after adjusting for age and smoking severity, whereas, African American youth are less likely than their ’other’ counterparts to use NRT. These findings suggest racial/ethnic disparities in accessing smoking cessation modalities among adolescents. Further research is needed to fully elucidate factors contributing to these differences in order to facilitate increased smoking cessation rates among all adolescents.
Ethn Dis. 2010 Spring;20(2):180-4.
设计：通过视频、电视和印刷宣传广告，募集研究参与者。对参与者采用预先筛选的问卷调查进行结构式访谈。
研究机构：受训者通过电话访谈收集吸烟者数据。
参与者：居住在巴尔的摩和马里兰州市区的、年龄为12～17岁的寻求戒烟的男性（38.2%）和女性（61.8%）共计1879名参与本研究。
干预措施：本项观察性研究未采用任何干预措施。
主要检测指标：通过对研究对象进行年龄、法格斯特伦尼古丁依赖测试（FTND）和种族进行分层后，研究受试者的NRT使用情况。
结果：研究对象的平均FTND 评分为5.7（SD=2.2）。大约有41％的吸烟者每天吸烟11～20支。采用NRT的年轻吸烟者，其年龄较未采用NRT的吸烟者年长，有统计学差异（15.9 vs 15.7岁; t-test= -2.60, P=0.01）。FTND 评分（检测尼古丁依赖的一个指标）在使用NRT的年轻人中较高（6.0 vs 5.6; t-test= -3.37, P= .001）。非洲裔美国人中，年轻吸烟者较相对应的欧洲裔美国年轻吸烟者较少使用NRT（33.0% vs 61.2%; chi2=16.09, P<.003）。通过逐步logistic回归分析，年龄、FTND 和种族是NRT使用的预测因子。
结论：我们结果显示不同年龄、不同FTND和不同种族年轻人群吸烟者中，其NRT使用存在差异。经过年龄和吸烟程度校正后，欧洲裔美国年轻吸烟者较其他相应人群吸烟者更常使用NRT，而非洲裔美国年轻吸烟者则较其他相应人群较少采用NRT。这些结果显示，在评价年轻吸烟者戒烟时，需考虑种族差异。对于造成这种差异的原因还需进一步进行研究，以便改善年轻吸烟者的戒烟。
（刘国梁 审校）
EthnDis.2010Spring;20(2):180-184.
Nicotine replacement therapy use among adolescent smokers seeking cessation treatment.
Botello-Harbaum M, Schroeder JR, Collins CC, Moolchan ET.
National Institutes of Health, National Institute of Child Health and Human Development, Intramural Research Program, USA.
Abstract
OBJECTIVE: To examine the correlates of prior nicotine replacement therapy (NRT) in an urban sample of adolescent smokers seeking smoking cessation treatment.
DESIGN: Adolescents were recruited via radio, TV and print advertisements for participation in treatment studies. Participants completed a structured interview using a prescreening questionnaire.
SETTING: Data were collected via a telephone interview by trained research personnel.
PARTICIPANTS: A sample (N=1879) cessation treatment-seeking volunteer boys (38.2%) and girls (61.8%) aged 12 to 17 years, from a diverse ethnic background residing in the Baltimore, Maryland metropolitan area.
INTERVENTIONS: No interventions were used in this observational study.
MAIN OUTCOME MEASURES: Use of NRT in adolescents stratified by age, Fagerstrom Test of Nicotine Dependence (FTND), and race/ethnicity.
RESULTS: The sample had a mean FTND score of 5.7 (SD = 2.2). About 41% smoked 11 to 20 cigarettes per day. Adolescent smokers who had used NRT were statistically but only marginally older than those who had not (15.9 vs 15.7 years; t-test= -2.60, P=0.01). FTND score, a measure of nicotine dependence, was higher among those who had used NRT (6.0 vs 5.6; t-test= -3.37, P= .001). African American adolescents were less likely to have used NRT than their European American counterparts (33.0% vs 61.2%; chi2=16.09, P<.003). After stepwise logistic regression analyses, age, FTND and race/ethnicity remained predictors of NRT use.
CONCLUSION: Our results show differences in NRT use patterns based on age, FTND, and race/ethnicity. European American youths are more likely than their ’other’ counterparts to use NRT, after adjusting for age and smoking severity, whereas, African American youth are less likely than their ’other’ counterparts to use NRT. These findings suggest racial/ethnic disparities in accessing smoking cessation modalities among adolescents. Further research is needed to fully elucidate factors contributing to these differences in order to facilitate increased smoking cessation rates among all adolescents.
Ethn Dis. 2010 Spring;20(2):180-4.
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