戒烟的一般做法:在实践中强化支持戒烟的一项集群、随机试验

2015/04/27

   摘要
   目的:
旨在评估个体化支持戒烟的获取和有效性,主要由专科护士(PN)提供,并对支持戒烟的其他形式进行比较。
   方法:三项集群、随机、对照试验在悉尼和墨尔本市的101项一般做法中的2390例吸烟者中完成。将戒烟热线的转介和常规治疗作为对照组,与PN干预的戒烟相比较。戒烟的药物治疗被推荐到所有群体。使用3个月和12个月随访期的自我报告对结果进行评估。另外对采用的干预手段也进行了报道。
   结果:三组在基线水平相似。随访12个月为82%。各组3个月持续性和点戒烟率分别为:PN干预组为13.1%和16.3%;戒烟热线转介率为10.8%和14.2%;通常的GP护理治疗为11.4%和15.0%。12个月时,比例分别为:PN干预组5.4%和17.1%;戒烟热线转介率为4.4%和18.8%;通常的GP护理为2.9%和16.4%。PN干预组只有43%的患者需要护士。多层次的回归分析表明,整体上干预是没有影响的,但获得部分或完全PN干预支持的患者更可能报告持续性戒烟率[部分支持组的比值比(OR)为2.27;完整支持组的比值比(OR)为5.34]。
   结论:结果表明,在意向治疗分析时各组无差异。获得更多强化PN干预治疗的患者更可能戒烟。这可能与患者的动机或PN诱导支持戒烟的效果相关。


 

(苏欣 审校)
Fam Pract. 2015 Feb 9. pii: cmu089. [Epub ahead of print]



 

Quit in general practice: a cluster randomized trial of enhanced in-practice support for smoking cessation.
 

Zwar NA1, Richmond RL2, Halcomb EJ3, Furler JS4, Smith JP5, Hermiz O6, Blackberry ID4, Jayasinghe UW6, Borland R7.

ABSTRACT
OBJECTIVES:
To evaluate the uptake and effectiveness of tailored smoking cessation support, provided primarily by the practice nurse (PN), and compare this to other forms of cessation support.
METHODS: Three arm cluster randomized controlled trial conducted in 101 general practices in Sydney and Melbourne involving 2390 smokers. The Quit with PN intervention was compared to Quitline referral and a usual care control group. Smoking cessation pharmacotherapy was recommended to all groups. Outcomes were assessed by self-report at 3- and 12-month follow-up. Uptake of the interventions is also reported.
RESULTS: The three groups were similar at baseline. Follow-up at 12 months was 82%. The sustained and point prevalence abstinence rates, respectively, at 3 months by group were: PN intervention 13.1% and 16.3%; Quitline referral 10.8% and 14.2%; Usual GP care 11.4% and 15.0%. At 12 months, the rates were: PN intervention 5.4% and 17.1%; Quitline referral 4.4% and 18.8%; Usual GP care 2.9% and 16.4%. Only 43% of patients in the PN intervention group attended to see the nurse. Multilevel regression analysis showed no effect of the intervention overall, but patients who received partial or complete PN support were more likely to report sustained abstinence [partial support odds ratio (OR) 2.27; complete support OR 5.34].
CONCLUSION: The results show no difference by group on intention to treat analysis. Those patients who received more intensive PN intervention were more likely to quit. This may have been related to patient motivation or an effect of PN led cessation support.

Fam Pract. 2015 Feb 9. pii: cmu089. [Epub ahead of print]


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